NICOTINAMIDE MONONUCLEOTIDE (NMN) REVIEW /WHAT IS NICOTINAMIDE MONONUCLEOTIDE?
Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme that consists of adenine and nicotinamide, it is found in every cell of all living organisms. NAD+ has been shown to be essential for supporting bodily functions by enhancing sensitivity, improving energy metabolism, and improving stress resistance. It also participates in genome protection through DNA repair, is neuroprotective, and is required for SIRTUIN activation.nmn powder
NAD+ helps enzymes transfer electrons during redox reactions to form ATP and is thus an aid to energy supply. However, levels decline with age – the NAD+ in an older person’s cells falls by more than 50%, which means the mitochondria then produce less energy and cells age. But fortunately, this process is not irreversible and intercellular energy mechanisms can be restored if levels of NAD+ are increased.
In addition, NAD is an essential cofactor of key longevity enzymes called sirtuins, activating them directly. Sirtuins play a fundamental role in life expectancy as they deactivate particular genes that lead to ageing via inflammatory processes.
Thus the combined fall in sirtuins 1 and 3, and in NAD+, can cause cerebral degeneration, vascular inflammation, fatigue, loss of muscle strength, increased fat stores around the liver and abdomen and insulin resistance leading directly to metabolic syndrome.
Our bodies can produce NAD+ from a variety of different elements, but as we just said, our levels of NAD+ drop significantly with age. “NAD+ levels tend to drop by as much as 50% as we get older”, according to Dr. David Agus a world leading Physician in Cancer treatment and a pioneer in Biomedical Research.